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How Needle Gauge Affects Injection Comfort and Efficacy

December 11, 2024

When it comes to injections, the needle gauge plays an important role in both comfort and efficacy. Whether you are administering medication or drawing blood, selecting the correct needle gauge can make a world of difference in terms of patient experience and overall clinical outcomes. While it may seem like a small detail, the gauge, or diameter of the needle, directly affects how smoothly the needle penetrates the skin, the flow rate of the fluid, and the level of discomfort experienced by the patient.

What is Needle Gauge?

Needle gauge refers to the diameter of the needle and is typically measured in gauge units (G). The higher the gauge number, the smaller the diameter of the needle. For instance, a 25G needle is thinner than a 21G needle. The size of the gauge chosen depends on the type of injection being administered, the viscosity of the medication, and the location of the puncture site.

For example, the RELI® Conventional Hypodermic Needle offers various gauge sizes to accommodate different medical needs. Its proprietary regular wall design enhances flow and durability, and the siliconized three-facet bevel facilitates smooth insertion. This combination minimizes discomfort while maintaining effectiveness, making it an excellent choice for a wide range of applications.

Needle Gauge and Injection Comfort

For patients, injection comfort often comes down to the size of the needle. Thinner needles, such as those with higher gauges (e.g., 25G or 27G), tend to cause less pain and discomfort because they create a smaller puncture wound in the skin. This is especially important for patients who require frequent injections, such as those managing diabetes or undergoing long-term treatments. However, while thinner needles are less invasive, they may not always be the best choice for every type of medication or procedure.

Viscous medications, such as certain oils, hormones, or biologics, require lower-gauge (thicker) needles to promote smooth and efficient flow. These medications may clog higher-gauge needles, leading to increased pressure during administration, which could result in an uncomfortable experience for both the healthcare provider and the patient. In contrast, thinner medications, like vaccines or insulin, can be administered with higher-gauge needles, where the focus is on minimizing the puncture size to reduce pain and tissue trauma.

For example, when administering medications using the RELI® Conventional Hypodermic Needle with Pre-attached Luer Lock Syringe, the needle’s design reduces insertion force, enhancing patient comfort without sacrificing performance. Additionally, the RELI® Luer Lock Syringe makes for a secure connection between the needle and syringe, minimizing the chances of leakage or disconnection during the injection process. This feature is crucial in clinical settings where precision is paramount, as even minor inaccuracies can compromise the effectiveness of the medication.

Another factor that contributes to the importance of gauge selection is the type of tissue being targeted. For example, subcutaneous injections, which deliver medication just under the skin, typically benefit from higher-gauge needles. These needles are better suited for penetrating the delicate subcutaneous tissue without causing unnecessary pain. Conversely, intramuscular injections, which deliver medication into thicker, more vascular muscle tissue, often require lower-gauge needles to ensure proper depth and distribution of the medication. In both cases, using the right needle gauge helps deliver the medication effectively while minimizing discomfort and potential complications such as tissue damage or irritation.

According to a study by Loureiro et al. published in the Journal of Current Glaucoma Practice, comparing the effects of 30-gauge and 27-gauge needles on intraocular pressure (IOP) rise and patient pain after intravitreal injections (IVI) of bevacizumab revealed that both needle sizes caused a significant rise in IOP post-injection. Although the 27-gauge needle resulted in a slightly lower post-injection IOP and less IOP variation compared to the 30-gauge needle, the differences were not statistically significant. Pain levels, measured using the visual analog scale (VAS), were similar between the two groups. The findings suggest that while both needle sizes are generally well tolerated, 27-gauge needles might be preferable for patients at higher risk of IOP spikes, such as those with glaucoma. (1)

By carefully selecting the appropriate needle gauge and using high-quality products like those offered by MYCO Medical, healthcare providers can significantly enhance the patient experience. Whether the focus is on minimizing pain during routine injections or ensuring efficient delivery of more complex medications, understanding the nuances of needle design and gauge selection plays a critical role in achieving both comfort and clinical efficacy.

Needle Gauge and Injection Efficacy

While comfort is important, efficacy cannot be compromised. The size of the needle must align with the medication or fluid being injected to assist with proper delivery. Thicker needles are often used for more viscous medications or when rapid infusion is required, while thinner needles are better suited for subcutaneous injections or drawing blood.

Choosing the Right Gauge for Different Procedures

Choosing the appropriate needle gauge depends largely on the procedure. For intramuscular injections, a thicker needle, such as 22G or 21G, is commonly used, as the medication must penetrate deeper into the muscle tissue. On the other hand, insulin or vaccines, which are injected subcutaneously, typically use higher-gauge, thinner needles (25G to 30G), which are less invasive and more comfortable for the patient.

MYCO Medical’s line of needles and syringes comes with a variety of gauge options and color-coded hubs, making it easy for healthcare professionals to quickly identify the appropriate size. Its OSHA-compliant safety-engineered sharp promotes not only patient comfort but also healthcare worker safety by reducing the risk of needle-stick injuries.

Conclusion

Selecting the correct needle gauge is more than a matter of patient comfort—it’s integral to the efficacy and safety of medical procedures. The choice of gauge affects how medications are administered, influencing not just the immediate experience of the patient but also the long-term effectiveness of treatments. A well-chosen needle can minimize trauma and anxiety, fostering a more positive healthcare experience.

Using high-quality products like MYCO Medical’s ensures that healthcare professionals can tailor their tools to the specific needs of each procedure. These products are engineered to meet rigorous standards for both comfort and performance. This is particularly important for patients who may have a fear of needles or those requiring multiple injections, such as those undergoing chronic treatments.

Understanding the relationship between needle gauge and injection outcomes allows medical professionals to improve both the patient experience and the efficiency of their practices. Proper training and awareness of the nuances of needle selection can lead to better management of pain and anxiety, contributing to a more favorable perception of medical procedures. Furthermore, well-informed decisions about needle gauge can also enhance patient safety by reducing the risk of complications associated with improper injections, such as extravasation or infection.

Ultimately, ensuring better results and higher levels of care hinges on the integration of knowledge and high-quality products into everyday practice. Healthcare providers who prioritize both the technical and emotional aspects of patient care can foster a more supportive environment, leading to improved health outcomes and overall patient satisfaction. As the healthcare landscape continues to evolve, so too must the approaches we take in delivering care, with an emphasis on precision, safety, and compassion at the forefront of our practices.

Get Needles, Syringes, and More from MYCO Medical

MYCO Medical is a NMSDC Certified Diversity Supplier specializing in delivering premium medical devices and disposables to health systems throughout the United States and Canada. Since 1993, we've helped countless hospitals and care centers overcome their biggest supply chain challenges and build a consistent stream of high-quality medical supplies.

Our needles and syringes are made with effective safety mechanisms to help provide optimal sharps protection and minimize the risk of accidental needle stick injury. All needles are manufactured to strict quality standards using computerized grinding and 100% visual camera inspection to ensure sharp, consistent, and high-quality needles in FDA-inspected ISO 13485 certified facilities which utilize good manufacturing practices per USFDA standards.

Browse our wide selection of durable Luer lock syringes, insulin syringes, hypodermic syringes, hypodermic needles, safety syringes, specialty needles and more, or contact our sales team today and receive a free complimentary sample and quote for our most popular products.

Browse All Needles & Syringe Products from MYCO Medical

Reference:

1. Loureiro, M., Matos, R., Sepúlveda, P., & Meira, D. (2017). Intravitreal injections of bevacizumab: the impact of needle size in intraocular pressure and pain. Journal of Current Glaucoma Practice, 11(2), 38-41. https://doi.org/10.5005/jp-journals-10028-1220

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